Wednesday, April 25, 2012

Viral kinetics: methodology

Measuring VL at baseline, as well as early after treatment
initiation may help to predict response and determine the
optimal length of therapy. As shown in chapter 1, in order to
maximize treatment effectiveness, while minimizing toxicity,
the optimal duration of PegIFN/RBV therapy is determined by
viral genotype, with additional guidance provided by the ontreatment
response (RVR being an earlier predictor of treatment
success and EVR an accurate predictor of treatment failure).

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